Clock gene expression profiles in the hypothalamus (A) and skeletal muscle (B) of EsrCre/flox/TM mice.

<p>PPARγ^f/f/TM and EsrCre/flox/TM mice were sacrificed at 6-h intervals. The hypothalamus and skeletal muscle were harvested for qRT-PCR analysis of canonical clock gene expression. For each gene, the lowest level of mRNA expression was set to 1. N = 6–8 per group.