<p>Caco-2 monolayer that reached confluence on transwell plate was exposed with either 10 µM of Butaprost (EP2 specific agonist) or 50 µM of AH6809 (EP2 antagonist) on the apical side and TER (Ω/cm<sup>2</sup>) measured at the time indicated for each group, compared to control and depicted as % of control. The mean baseline TER at the start of the experiment was 1025.5±71.5 Ω/cm<sup>2</sup>. ★ p<0.05; ★★ p<0.01 and ★★★ p<0.001.</p
(A) Experimental timeline of 1,25(OH)2D3 and FeCl3 treatment (please see text for detail). (B–E) Tra...
<p><b>(A)</b> Representative photographs of colons; “Veh” indicates vehicle and “EP4” indicates EP4 ...
The isoprostanes, which differ from prostaglandins by the cis orientation of their side chains, are ...
<p>(A) TcdA/B-induced (10 μg/mL) FITC-flux is significantly reduced by the selective P2Y<sub>6</sub>...
(A) Timeline of Experiment 1. (B) Transepithelial calcium flux and (C–E) epithelial electrical param...
<p>(<b>A</b>) Caco-2 cells were stimulated by hypertonic stress (100 mM NaCl) during 24 h after pre-...
<p>A) BSE and AKBA; B) BSE and AKBA with H<sub>2</sub>O<sub>2</sub> (<sup>+++</sup><i>p</i><0.001 H<...
(A) Timeline of Experiment 2. (B) Transepithelial calcium flux and (C–E) epithelial electrical param...
<p>(A) IL-6 caused a dose-dependent decrease in TER over 48-h experimental period (<i>n</i> = 4). *<...
<p><b>A)</b> Caco-2 cells were incubated with T or T pre-incubated with protease inhibitors (PI) or ...
<p> <i>A</i>–<i>B</i>: Caco-2 P-MLC immunoblot and relative band densities. Cytomix-stimulation incr...
<p>A) basal condition. B) BSE and AKBA + H<sub>2</sub>O<sub>2</sub> (<sup>+++</sup><i>p</i><0.001 H<...
<p>Cell layers were treated with 0.05-RAMEB (FR) alone or in the presence of 5 mM RAMEB (FRR). Untre...
Epithelial damage caused by intestinal permeation enhancers is a source of debate over their safety....
(A) Timeline of Experiment 3. (B) Transepithelial calcium flux and (C–E) epithelial electrical param...
(A) Experimental timeline of 1,25(OH)2D3 and FeCl3 treatment (please see text for detail). (B–E) Tra...
<p><b>(A)</b> Representative photographs of colons; “Veh” indicates vehicle and “EP4” indicates EP4 ...
The isoprostanes, which differ from prostaglandins by the cis orientation of their side chains, are ...
<p>(A) TcdA/B-induced (10 μg/mL) FITC-flux is significantly reduced by the selective P2Y<sub>6</sub>...
(A) Timeline of Experiment 1. (B) Transepithelial calcium flux and (C–E) epithelial electrical param...
<p>(<b>A</b>) Caco-2 cells were stimulated by hypertonic stress (100 mM NaCl) during 24 h after pre-...
<p>A) BSE and AKBA; B) BSE and AKBA with H<sub>2</sub>O<sub>2</sub> (<sup>+++</sup><i>p</i><0.001 H<...
(A) Timeline of Experiment 2. (B) Transepithelial calcium flux and (C–E) epithelial electrical param...
<p>(A) IL-6 caused a dose-dependent decrease in TER over 48-h experimental period (<i>n</i> = 4). *<...
<p><b>A)</b> Caco-2 cells were incubated with T or T pre-incubated with protease inhibitors (PI) or ...
<p> <i>A</i>–<i>B</i>: Caco-2 P-MLC immunoblot and relative band densities. Cytomix-stimulation incr...
<p>A) basal condition. B) BSE and AKBA + H<sub>2</sub>O<sub>2</sub> (<sup>+++</sup><i>p</i><0.001 H<...
<p>Cell layers were treated with 0.05-RAMEB (FR) alone or in the presence of 5 mM RAMEB (FRR). Untre...
Epithelial damage caused by intestinal permeation enhancers is a source of debate over their safety....
(A) Timeline of Experiment 3. (B) Transepithelial calcium flux and (C–E) epithelial electrical param...
(A) Experimental timeline of 1,25(OH)2D3 and FeCl3 treatment (please see text for detail). (B–E) Tra...
<p><b>(A)</b> Representative photographs of colons; “Veh” indicates vehicle and “EP4” indicates EP4 ...
The isoprostanes, which differ from prostaglandins by the cis orientation of their side chains, are ...