(A) Timeline of Experiment 3. (B) Transepithelial calcium flux and (C–E) epithelial electrical parameters (PD, Isc, and TER) across Caco-2 monolayers pretreated with 10 nM 1,25(OH)2D3 for 72 h and then exposed to 2–200 μM CFTR inhibitor (CFTRinh-172) on the apical side. ***p †p †††p 2D3-treated group (closed bar, one-way ANOVA with Tukey’s multiple comparison test).</p
(A) and (B) Whereas 10 μM CFTRinh-172 was reported to eliminate about 90% of WT-hCFTR current [52], ...
The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a cAMP-regulated Cl- chann...
(a) Time-dependent Fe2+ uptake by HEK cells expressing WT Fpn. Approximately 100 μM Fe2+ (stabilized...
(A) Experimental timeline of 1,25(OH)2D3 and FeCl3 treatment (please see text for detail). (B–E) Tra...
(A) Experimental timeline (please see text for detail). (B–E) Transepithelial calcium transport and ...
(A) Experimental timeline (please see text for detail). (B–E) Transepithelial calcium transport and ...
(A) The architecture of CFTR and location of the proposed CFTRinh-172 (magenta)- and genistein (gree...
(A) Timeline of Experiment 2. (B) Transepithelial calcium flux and (C–E) epithelial electrical param...
(A) Transepithelial calcium transport across Caco-2 monolayers with or without 0.5 mM Asc pre-treatm...
This study compares the effect of three chemically unrelated cystic fibrosis transmembrane conductan...
<p>(<b>A</b>) Primary HBE cells were treated with 2% CSE or vehicle control for 24 h, then studied u...
The cystic fibrosis transmembrane conductance regulator (CFTR) anion channel and the epithelial Na+ ...
(A) Timeline of Experiment 1. (B) Transepithelial calcium flux and (C–E) epithelial electrical param...
<p>Cell layers were treated with 0.05-RAMEB (FR) alone or in the presence of 5 mM RAMEB (FRR). Untre...
Effective and specific inhibition of the cystic fibrosis transmembrane conductance regulator (CFTR) ...
(A) and (B) Whereas 10 μM CFTRinh-172 was reported to eliminate about 90% of WT-hCFTR current [52], ...
The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a cAMP-regulated Cl- chann...
(a) Time-dependent Fe2+ uptake by HEK cells expressing WT Fpn. Approximately 100 μM Fe2+ (stabilized...
(A) Experimental timeline of 1,25(OH)2D3 and FeCl3 treatment (please see text for detail). (B–E) Tra...
(A) Experimental timeline (please see text for detail). (B–E) Transepithelial calcium transport and ...
(A) Experimental timeline (please see text for detail). (B–E) Transepithelial calcium transport and ...
(A) The architecture of CFTR and location of the proposed CFTRinh-172 (magenta)- and genistein (gree...
(A) Timeline of Experiment 2. (B) Transepithelial calcium flux and (C–E) epithelial electrical param...
(A) Transepithelial calcium transport across Caco-2 monolayers with or without 0.5 mM Asc pre-treatm...
This study compares the effect of three chemically unrelated cystic fibrosis transmembrane conductan...
<p>(<b>A</b>) Primary HBE cells were treated with 2% CSE or vehicle control for 24 h, then studied u...
The cystic fibrosis transmembrane conductance regulator (CFTR) anion channel and the epithelial Na+ ...
(A) Timeline of Experiment 1. (B) Transepithelial calcium flux and (C–E) epithelial electrical param...
<p>Cell layers were treated with 0.05-RAMEB (FR) alone or in the presence of 5 mM RAMEB (FRR). Untre...
Effective and specific inhibition of the cystic fibrosis transmembrane conductance regulator (CFTR) ...
(A) and (B) Whereas 10 μM CFTRinh-172 was reported to eliminate about 90% of WT-hCFTR current [52], ...
The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a cAMP-regulated Cl- chann...
(a) Time-dependent Fe2+ uptake by HEK cells expressing WT Fpn. Approximately 100 μM Fe2+ (stabilized...