Expression profile of miRNAs and their target genes.

<p>A. Heat map representing the differential expression of miRNAs during physiological cardiac hypertrophy. miRNAs with higher read counts (> 1000) were considered for differential expression analysis. Analysis was statistically evaluated by Poisson distribution. B. Validation of expression profile of miRNAs by qPCR. U87 served as house keeping gene. Data represent the mean of biological triplicates with technical duplicates. Asterisk represents the statistical significance by One way ANOVA test at p-value <0.05. Double asterisk represents statistical significance at p-value < 0.005. C. Expression of target genes of miRNAs. The values were represented as mean±SE of three biological triplicates with technical duplicates. GAPDH served as house keeping gene. Asterisk represents the statistical significance by One way ANOVA test at p-value <0.05. Double asterisk represents statistical significance at p-value < 0.005.