Cytotoxicity of compounds in RMS cells and normal human fibroblast cells.

<p>(A) Chemical structures of anti-RMS hits. (B) IC₅₀ values of the compounds in RD and NHFB cells. *, The selectivity index was calculated by dividing the IC₅₀ in NHFB cells by the IC₅₀ in RD cells. (C) The IC₅₀ values of MHPT in SJ-RH30 RMS cells and the normal human fibroblast cell lines MRC-5 and WI-38. #, the selectivity index was calculated by dividing the IC₅₀ in MRC-5 cells by the IC₅₀ in SJ-RH30 cells.