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Cytotoxicity of the selected MtTopoI inhibitor compounds in human cell lines.

Csilla Temesszentandrási-Ambrus (5721017)
Szilárd Tóth (4063186)
Rinkee Verma (5721020)
Péter Bánhegyi (5721023)
István Szabadkai (5721026)
Ferenc Baska (1822432)
Csaba Szántai-Kis (723330)
Ruben C. Hartkoorn (1327599)
Mary A. Lingerfelt (3630844)
Balázs Sarkadi (120135)
Gergely Szakács (3177213)
László Őrfi (554937)
Valakunja Nagaraja (9507)
Sean Ekins (162)
Ágnes Telbisz (4775190)

Publication date

September 2018

DOI

10.1371/journal.pone.0202749.t003

Publisher

Public Library of Science (PLoS)

Abstract

Cytotoxicity of the selected MtTopoI inhibitor compounds in human cell lines.</p

Extracted data

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Chemomedulatory effects of test compounds on the cytotoxicity parameters of PTX against LS-174T cell line.

Moustafa E. El-Araby (3626396)
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Maan T. Khayat (3626402)
Hanan A. Assiri (3626405)
Ahmed M. Al-Abd (465677)

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PND cytotoxic concentration 50% (CC50) and selective cytotoxic index (SCI) on a panel of human cell lines.

Paulina J. Villanueva (5931740)
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PND cytotoxic concentration 50% (CC50) and selective cytotoxic index (SCI) on a panel of human cell ...

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Manuela Voráčová (4672480)
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Hannah Goovaerts (4672489)
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<p>Antiproliferative and cytotoxic effect of compound 5 on different cell lines.</p

Cytotoxic activity against HeLa cell line, calculated for all samples tested.

Dawid Lewandowski (734993)
Piotr Ruszkowski (734995)
Anita Pińska (734996)
Grzegorz Schroeder (623308)
Joanna Kurczewska (766606)

July 2015

<p>Cytotoxic activity against HeLa cell line, calculated for all samples tested.</p

Determination of cytotoxicity of the inhibitors by MTT cytotoxicity assay.

Renu Dharra (4413280)
Sakshi Talwar (4413277)
Yogesh Singh (109219)
Rani Gupta (423009)
Jeffrey D. Cirillo (376505)
Amit K. Pandey (253660)
Mahesh Kulharia (2412658)
Promod K. Mehta (4413283)

September 2017

<p>Survival of HeLa cells in the presence of 1X and 5X MIC concentrations of inhibitors. INH was tak...

Cytotoxic activity against KB cell line, calculated for all samples tested.

Dawid Lewandowski (734993)
Piotr Ruszkowski (734995)
Anita Pińska (734996)
Grzegorz Schroeder (623308)
Joanna Kurczewska (766606)

July 2015

<p>Cytotoxic activity against KB cell line, calculated for all samples tested.</p

Mammalian Cytotoxicity Study of Novel Organometallic Complexes

Harrison, Nathan
Leach, Caleb
Lusk, Kyle
Waynant, Kris
Cornell, Ken

April 2021

Antibiotic resistance is becoming more and more prevalent in our society to the point that even simp...

Cytotoxic activity of temporins SHa and analogs against human cells and rat erythrocytes.

Zahid Raja (444869)
Sonia André (444870)
Feten Abbassi (669100)
Vincent Humblot (1664041)
Olivier Lequin (469727)
Tahar Bouceba (131137)
Isabelle Correia (1394596)
Sandra Casale (1613950)
Thierry Foulon (86631)
Denis Sereno (233155)
Bruno Oury (444872)
Ali Ladram (444873)

March 2017

<p>Cytotoxic activity of temporins SHa and analogs against human cells and rat erythrocytes.</p

MTT assay to evaluate the cytotoxicity of the compounds towards Raw264.7 cells.

Hai-Jing Zhong (118092)
Li-Juan Liu (293637)
Cheong-Meng Chong (517812)
Lihua Lu (476939)
Modi Wang (393693)
Daniel Shiu-Hin Chan (118095)
Philip Wai Hong Chan (545653)
Simon Ming-Yuen Lee (545654)
Dik-Lung Ma (103041)
Chung-Hang Leung (118097)

April 2014

<p>Cells were incubated with the indicated concentrations of compounds for 18λ = 570 nm after the ad...

Cytotoxic effect (IC<sub>50</sub>) of MTA and DIG-MSK against cancer cell lines and endothelial cell lines.

Azahara Fernández-Guizán (640357)
Alejandro López-Soto (640358)
Andrea Acebes-Huerta (640351)
Leticia Huergo-Zapico (640350)
Mónica Villa-Álvarez (5665726)
Luz-Elena Núñez (169843)
Francisco Morís (169876)
Segundo Gonzalez (640359)

November 2015

<p>Ns: Non significant</p><p>Cytotoxic effect (IC<sub>50</sub>) of MTA and DIG-MSK against cancer ce...

INTERACTION AND CYTOTOXICITY OF COMPOUNDS

Cell Lines
Rishan Singh

January 2014

The interactions of compounds on human cell lines are either influenced by the composition of substa...

Cytotoxicity in human cells.

Parvin Abraham (742957)
Anand Sundaram (742958)
Asha R (742959)
Reshmy V (742960)
Sanil George (742961)
K. Santhosh Kumar (742962)

May 2015

<p>The values represent averages ± s.d from three separated experiments.</p><p>Cytotoxicity in human...

Cytotoxicity of compounds in RMS cells and normal human fibroblast cells.

Yan Mu (713266)
Yin Liu (50073)
Liwen Li (491987)
Cong Tian (130440)
Hongyu Zhou (352858)
Qiu Zhang (239441)
Bing Yan (170259)

March 2015

<p>(A) Chemical structures of anti-RMS hits. (B) IC<sub>50</sub> values of the compounds in RD and N...

<i>In vitro</i> inhibitory effects of compounds 1a-2b against the proliferation of three human cancer cell lines.

Lan Wu (326399)
Kai Bao (700307)
Rui Song (331963)
Defa Wang (1269894)
Lei Zhang (38117)
Weiyun Wang (2889659)
Weige Zhang (752458)
Wen Bin (2889662)

July 2016

<p><i>In vitro</i> inhibitory effects of compounds 1a-2b against the proliferation of three human ca...

Anti-HIV and cytotoxic properties of organotellurium compounds in PHA-stimulated PBMCs.

Kathrin Reiser (606411)
Leen Mathys (589241)
Sophie Curbo (386586)
Christophe Pannecouque (496139)
Sam Noppen (253207)
Sandra Liekens (355811)
Lars Engman (1292892)
Mathias Lundberg (85855)
Jan Balzarini (161754)
Anna Karlsson (21145)

January 2016

<p>Anti-HIV and cytotoxic properties of organotellurium compounds in PHA-stimulated PBMCs.</p