No neuronal loss or neurodegeneration was detected in SNpc in transgenic mice.
- Marta Garcia-Miralles (716034)
- Janaky Coomaraswamy (195660)
- Karina Häbig (716035)
- Martin C. Herzig (164996)
- Natalja Funk (56294)
- Frank Gillardon (217954)
- Martina Maisel (716036)
- Mathias Jucker (528697)
- Thomas Gasser (33499)
- Dagmar Galter (225917)
- Saskia Biskup (40279)
Publication date
April 2015
DOIAbstract
<p><b>A:</b> Representative coronal section of midbrain sections from 12- to 13-month-old non-tg, LRRK2 and GS-LRRK2 (line 2) transgenic mice immunostained for TH. (Scale bars: 100μm). <b>B:</b> Cell counts of TH+ and Nissl+ neurons in SNpc from non-tg, LRRK2 and GS-LRRK2 transgenic mice. Data represent mean ± SEM; transgenic mice n = 2, non-tg mice n = 3. <i>n</i>.<i>s</i> = not significant, (one-way ANOVA, Tukey’s <i>post hoc</i> analysis).</p
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