Induction of apoptotic signaling.

<p>Western Blots show an increase of caspase 3 expression (A) and PARP cleavage (D) in SAH animals (Location of ICP-probe is hallmarked (+)). Immunohistochemical staining for caspase 3 (C) confirms these results (right lower corner: bar indicates 20 μm). Semiquantitative analysis of protein expression demonstrates significant increase of caspase 3 (B) and PARP cleavage (E) in SAH animals (independent from technique). (*** p<0.001; ** p<0.01; * p<0.05; # p>0.05)