In-vitro stimulation of whole blood.

<p>Stimulation experiments with IL-6, LPS, NGAL or their combinations with a total numbers of n = 4 are presented. (A) NGAL levels in vehicle controls (open bar) and after stimulation with LPS (grey filled bar), IL-6 (black filled bar), and after stimulation with only NGAL (open, striped bar), NGAL + LPS (grey, striped bar) and NGAL + IL-6 (black, striped bar). (B) Cytokine levels of IL-6 and IL-8 in control (open bars) and after stimulation with IL-6 (black) or NGAL (grey). (C) Cytokine levels of IL-6, IL-8, IL-10 as well as levels of LDH in control (open bars) and after stimulation with LPS (black) or LPS+NGAL (grey). * <i>P</i><0.05 compared to vehicle control or indicated by clamp to corresponding group. Bars and error bars represent median values and interquartile range.