VEGF expression in aorta of apoE^-/- mice treated with CIT.

<p>(A) Immunohistochemical staining of aortic sections (blue = nuclei, brown = target protein, 100×). (B) Integral optical density (IOD) values of VEGF. Data are presented as mean ± SEM (n = 10). (C) The concentrations of VEGF in serum of apoE^<b>-/-</b> mice(n = 10). The statistical analyses of one-way analysis of variance (ANOVA) and Student-Newman-Keuls (SNK) multiple comparison were performed to determine the significant difference among the three groups. *<i>P</i> < 0.05, **<i>P</i> < 0.01 versus vehicle-treated group; ^<b>#</b><i>P</i> < 0.05, ^<b>##</b><i>P</i> < 0.01 versus low dosage CIT treatment group.