Measured vascular volumes (<i>V_v</i>) in naïve and anti-VEGF-administered mice.

<p><i>Note:</i> Literature (Lit.) values are listed for comparison. Nude mice (n = 5) were naïve or administered a single, intravenous bolus dose (10 mg/kg) of the cross-species anti-VEGF antibody <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017874#pone.0017874-Liang1" target="_blank">[12]</a>, B20-4.1, 24 h prior to assay. All values are reported in µL/g. Values of <i>V_v</i> were measured using both direct and indirect RBC labeling methods <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017874#pone.0017874-Boswell2" target="_blank">[2]</a>. Note that the assay method can greatly influence measured <i>V_v</i>, especially in probe clearance organs.</p>a<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017874#pone.0017874-Park1" target="_blank">[39]</a>.</p>b<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017874#pone.0017874-Baxter1" target="_blank">[5]</a>.</p>c<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017874#pone.0017874-Brown1" target="_blank">[3]</a>.</p>d<p>Measured using ³H-inulin.</p>e<p>For well-perfused organs 10% vascular space is assumed <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017874#pone.0017874-Baxter1" target="_blank">[5]</a>.</p>f<p>Estimated from experimental IgG data at early time points <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017874#pone.0017874-Baxter1" target="_blank">[5]</a>.</p>g<p>Estimated from human data.</p>h<p>Data reproduced with permissions <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017874#pone.0017874-Boswell2" target="_blank">[2]</a>.