SB415286 partially reverses the HYS-32-inhibited astrocyte migration.

<p>(A) Control astrocytes (Con) or astrocytes treated with 5 μM HYS-32 (HYS), co-treated for 24 h with 5 μM HYS-32 and 20 μM SB415286 (HYS+SB), or treated with 20 μM SB415286 (SB) were analyzed with migration assay culture inserts 0, 12, 24, and 36 h after treatment (bars = 500 μm). (B) The data for the astrocytes migration area were collected from three independent experiments. *<i>p</i><0.01 compared to HYS using one-way ANOVA with Dunnett’s post-hoc test. The dotted lines marked the migration starting edge.