<p>(A) In response to increasing levels of step current injection (top), the model neuron soma has a firing threshold of ~80 pA (red), and fires a single action potential, even in response to currents of 3 times the threshold (blue). (B) Rebound spikes to negative current steps (expanded in bottom traces) during depolarisation in model neurons (thin blue line) and whole-cell recordings (thick grey line; from Dr Wen-Chang Li, unpublished).</p
<p><b>a</b> A current of 1 nA is injected into the dendritic compartment. This results in a depolari...
<p>Whole-cell patch-clamp recordings were made in current-clamp mode from the soma of neurons. Shown...
<p>(A) AP generated by a current clamp of 0.16 nA and 50 ms duration for experiments by Hayashi et a...
<p>(A) Current was injected into a single dIN in a population model of 30 dINs electrically coupled ...
<p>A: Neuronal morphology used to construct the model neurons. B, C: Experimental traces (top) and v...
<p>The neuron models and stimulation protocols were the same as those used in <a href="http://www.pl...
<p>(<b>A</b>–<b>B</b>). Patch-clamp recordings were made from iPS cells displaying an ovoid soma and...
<p>A) Typical response of a DMV neuron to current pulse injection. When depolarized from negative ho...
A: Somatic membrane potential time courses according to the Almog model in response to 2-ms square-p...
<p>(A) Resting potential measurements for three SN DA neurons as a function of time. After obtaining...
<p>A. Experimental traces showing current responses at the soma of a pyramidal neuron following gene...
<p><b>a</b>) the 3D reconstruction used in most simulations (<i>left</i>, cell ri06 from the neuromo...
<p>(A) The population of electrically-coupled dINs, onto which NMDA was perfused. (B) In life, perfu...
<p>(A) Box plots of the mean resting membrane potential (Rin) of MNs (blue box) and IML SPNs (black ...
<p><b>(a)</b> The somatic (black) and dendritic (red) response to three short current pulses at the ...
<p><b>a</b> A current of 1 nA is injected into the dendritic compartment. This results in a depolari...
<p>Whole-cell patch-clamp recordings were made in current-clamp mode from the soma of neurons. Shown...
<p>(A) AP generated by a current clamp of 0.16 nA and 50 ms duration for experiments by Hayashi et a...
<p>(A) Current was injected into a single dIN in a population model of 30 dINs electrically coupled ...
<p>A: Neuronal morphology used to construct the model neurons. B, C: Experimental traces (top) and v...
<p>The neuron models and stimulation protocols were the same as those used in <a href="http://www.pl...
<p>(<b>A</b>–<b>B</b>). Patch-clamp recordings were made from iPS cells displaying an ovoid soma and...
<p>A) Typical response of a DMV neuron to current pulse injection. When depolarized from negative ho...
A: Somatic membrane potential time courses according to the Almog model in response to 2-ms square-p...
<p>(A) Resting potential measurements for three SN DA neurons as a function of time. After obtaining...
<p>A. Experimental traces showing current responses at the soma of a pyramidal neuron following gene...
<p><b>a</b>) the 3D reconstruction used in most simulations (<i>left</i>, cell ri06 from the neuromo...
<p>(A) The population of electrically-coupled dINs, onto which NMDA was perfused. (B) In life, perfu...
<p>(A) Box plots of the mean resting membrane potential (Rin) of MNs (blue box) and IML SPNs (black ...
<p><b>(a)</b> The somatic (black) and dendritic (red) response to three short current pulses at the ...
<p><b>a</b> A current of 1 nA is injected into the dendritic compartment. This results in a depolari...
<p>Whole-cell patch-clamp recordings were made in current-clamp mode from the soma of neurons. Shown...
<p>(A) AP generated by a current clamp of 0.16 nA and 50 ms duration for experiments by Hayashi et a...