Cytokine production by spleen and CNS cell cultures.

<p>IFN-γ (<b>A</b> and <b>E</b>), IL-17 (<b>B</b> and <b>F</b>), IL-6 (<b>C</b> and <b>G</b>) and IL-10 (<b>D</b> and <b>H</b>) levels were measured in spleen and CNS cell cultures stimulated with MOG. Comparisons between groups were made by one way ANOVA followed by Tukey’s test for parametric variables (<b>D, F</b> and <b>G</b>) and by Kruskal-Wallis followed by Dunn’s test for non-parametric variables (<b>A</b>, <b>B, C, E</b> and <b>H</b>). Data were presented by mean ± SE or medians (25–75% ranges) of 9 animals per group in spleen cultures or 4 pools (each pool contains cells from brain and spinal cord of 3 mice) per group in CNS cultures. * p<0.05. Data are representative of two independent experiments.