<p>Learning networks independently corresponds to setting λ<sub><i>p</i></sub> = 0 (the bottom left corner of each graph); the y-axis is the improvement in log likelihood over baseline. Our method improved on this baseline for all three gene sets we experimented with. The baseline of learning a single network for all tissues cannot be shown on this graph because its log likelihood is so low; we dropped it from further consideration in our analysis. The differing scales on the y-axes are due to the different sizes of the gene sets.</p
The x-axis represents the percentage of top gene/links used, the y-axis the z-score of observed vs. ...
Network inference, which is the reconstruction of biological networks from high-throughput data, can...
<p>PPV: Positive Predicted Value (or accuracy) defined as , where is true positive and is false po...
(A) Relationship between TF activity and target expression in B. subtilis 1 (blue) and in B. subtili...
a. Performance (AUC) of Lasso classification using individual genes in 12 networks. Numbers below ea...
<p><b>A.</b> 107 tissues were grouped into major body systems according to the anatomical hierarchic...
BACKGROUND: Sparse Gaussian graphical models are popular for inferring biological networks, such as ...
<p>In these plots, the y-axis shows the performance of the reconstructed network, measured by the AU...
<p>The confidences of the edges are represented as percentage of the edges that persisted across 20...
Figure S6. Degree distributions of the learned networks (from Pcorr, BN, GENIE3, SCODE and PIDC), re...
<p>Predicted networks were evaluated on the basis of two scoring metrics, (<b>a</b>) area under the ...
<p>(A) The integrated network is constructed from String and HumanNet; (B) The integrated network is...
<p>The legend shows the used sample sizes. Gene expression data were simulated for an Erdös-Rényi ne...
<p>A) Network edges were compared to a predicted transcription factor – target database. The number ...
<p>A solid line represents the performances of the proposed method. Dotted and dashed lines represen...
The x-axis represents the percentage of top gene/links used, the y-axis the z-score of observed vs. ...
Network inference, which is the reconstruction of biological networks from high-throughput data, can...
<p>PPV: Positive Predicted Value (or accuracy) defined as , where is true positive and is false po...
(A) Relationship between TF activity and target expression in B. subtilis 1 (blue) and in B. subtili...
a. Performance (AUC) of Lasso classification using individual genes in 12 networks. Numbers below ea...
<p><b>A.</b> 107 tissues were grouped into major body systems according to the anatomical hierarchic...
BACKGROUND: Sparse Gaussian graphical models are popular for inferring biological networks, such as ...
<p>In these plots, the y-axis shows the performance of the reconstructed network, measured by the AU...
<p>The confidences of the edges are represented as percentage of the edges that persisted across 20...
Figure S6. Degree distributions of the learned networks (from Pcorr, BN, GENIE3, SCODE and PIDC), re...
<p>Predicted networks were evaluated on the basis of two scoring metrics, (<b>a</b>) area under the ...
<p>(A) The integrated network is constructed from String and HumanNet; (B) The integrated network is...
<p>The legend shows the used sample sizes. Gene expression data were simulated for an Erdös-Rényi ne...
<p>A) Network edges were compared to a predicted transcription factor – target database. The number ...
<p>A solid line represents the performances of the proposed method. Dotted and dashed lines represen...
The x-axis represents the percentage of top gene/links used, the y-axis the z-score of observed vs. ...
Network inference, which is the reconstruction of biological networks from high-throughput data, can...
<p>PPV: Positive Predicted Value (or accuracy) defined as , where is true positive and is false po...