MCP-1 secretion was not affected by alterations in F-actin or α-tubulin structures.

<p>MCP-1 secretion from control and TREK-1 deficient cells was measured after exposure to cytochalasin D (Cyto D), jasplakinolide (Jasp), nocodazole (noco) with or without TNF-α for 2 (Fig 7A) or 6 hours (Fig 7B). *compared to untreated control cells; #compared to untreated TREK-1 deficient cells. n = 6–9.