<p>(A). Hepatic hydroxyl-proline content and qRT-PCR analysis of liver fibrosis and progenitor marker genes; (B). Liver sections from representative mice stained for markers of the fibroductular reaction (Sirius red, α-SMA, desmin, K19 and Sox-9) (left panels) and respective morphometry (right). Results normalized to chow-fed mice and graphed as mean±SEM. *<0.05 and **<0.005, control <i>versus</i> experimental diet; #<0.05 and ##<0.005, MCD <i>versus</i> Western diet.</p
<p>A. Liver fibrosis was determined by Sirius red staining (red) in <i>Nrd1<sup>+/+</sup></i> and <i...
<p>Mice were fed a western-type diet for 18 weeks, and received in the last 6 weeks either 0, 50 or ...
<p><b>(A)</b> Photomicrographs of Picro-Sirius red stain showing peri-cellular fibrosis. <b>(B)</b> ...
<p>(A). Liver to body weight (LBW) ratio, serum aminotransferases (ALT, AST) and alkaline phosphatas...
<p>(A). TUNEL assay and Western blot for caspase-2 and cleaved PARP; (B). qRT-PCR of macrophage mark...
<p><b>(A)</b> Histological analysis on Sirius Red stained livers revealed a progressive collagen dep...
Livers of mice in the 3 groups, RD46, WD38 & WD46, were fixed in buffered formalin, sectioned and st...
<p>CCL3 expression is increased in MCD-fed wild-type mice compared to untreated control (<b>A</b>). ...
<p>(A) Scoring of Masson's trichrome stained liver sections (means +/− SE). (B) Scoring of Sirius Re...
<p>Liver fibrosis as assessed by Sirius red staining (A-C, representative microphotographs), reticul...
<p>(A) Ratio of liver to body weight, (B) Hepatic triglyceride, and (C) AST values were analyzed in ...
<p>Body weight (A) and liver weight (B) of male MC4R-KO (MC) and wildtype (WT) mice fed a western di...
<p>Liver specimens were obtained and the total RNA was extracted from male wild type or <i>Tet-mev-1...
<p>(A) The effects of LY2405319 administration on MCD diet-induced liver fibrosis in mice. H&E stain...
<p><b>(A)</b> Immunohistochemical analysis on mouse liver specimens shows a progressive expansion in...
<p>A. Liver fibrosis was determined by Sirius red staining (red) in <i>Nrd1<sup>+/+</sup></i> and <i...
<p>Mice were fed a western-type diet for 18 weeks, and received in the last 6 weeks either 0, 50 or ...
<p><b>(A)</b> Photomicrographs of Picro-Sirius red stain showing peri-cellular fibrosis. <b>(B)</b> ...
<p>(A). Liver to body weight (LBW) ratio, serum aminotransferases (ALT, AST) and alkaline phosphatas...
<p>(A). TUNEL assay and Western blot for caspase-2 and cleaved PARP; (B). qRT-PCR of macrophage mark...
<p><b>(A)</b> Histological analysis on Sirius Red stained livers revealed a progressive collagen dep...
Livers of mice in the 3 groups, RD46, WD38 & WD46, were fixed in buffered formalin, sectioned and st...
<p>CCL3 expression is increased in MCD-fed wild-type mice compared to untreated control (<b>A</b>). ...
<p>(A) Scoring of Masson's trichrome stained liver sections (means +/− SE). (B) Scoring of Sirius Re...
<p>Liver fibrosis as assessed by Sirius red staining (A-C, representative microphotographs), reticul...
<p>(A) Ratio of liver to body weight, (B) Hepatic triglyceride, and (C) AST values were analyzed in ...
<p>Body weight (A) and liver weight (B) of male MC4R-KO (MC) and wildtype (WT) mice fed a western di...
<p>Liver specimens were obtained and the total RNA was extracted from male wild type or <i>Tet-mev-1...
<p>(A) The effects of LY2405319 administration on MCD diet-induced liver fibrosis in mice. H&E stain...
<p><b>(A)</b> Immunohistochemical analysis on mouse liver specimens shows a progressive expansion in...
<p>A. Liver fibrosis was determined by Sirius red staining (red) in <i>Nrd1<sup>+/+</sup></i> and <i...
<p>Mice were fed a western-type diet for 18 weeks, and received in the last 6 weeks either 0, 50 or ...
<p><b>(A)</b> Photomicrographs of Picro-Sirius red stain showing peri-cellular fibrosis. <b>(B)</b> ...