Normalization of mRNA expression of fibrotic markers after cessation of Ang II infusion.
- Anne-Roos S. Frenay (752766)
- Saleh Yazdani (297333)
- Miriam Boersema (534157)
- Anne Marijn van der Graaf (480821)
- Femke Waanders (752767)
- Jacob van den Born (167146)
- Gerjan J. Navis (153097)
- Harry van Goor (18163)
Publication date
June 2015
DOIAbstract
<p>mRNA expression of the fibrotic markers TGF-beta, Col4a1 and Col5a1 was upregulated under Ang II infusion (A, B, C). Eight weeks after stopping Ang II infusion, mRNA levels of all markers returned to control levels again. (#p<0.05, ##p<0.01 <i>vs</i>. control at time of biopsy; *p<0.05, **p<0.01 <i>vs</i>. Ang II at time of biopsy).</p
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