Effect of IFNγ in the presence and absence of TNFα on the release of CXCL9, CXCL10 and CXCL11 from BEAS-2B and primary human airway epithelial cells.

<p>BEAS-2B cells, n = 11 (open bars, panels a, c and e) or human primary airway epithelial cells from non-smokers (n = 4) (closed bars), smokers (n = 5) (horizontal lines) or patients with COPD (n = 7) (hatched bars) (panels b, d and f) were incubated for 20h in the absence or presence of IFNγ (10ng/ml) or IFNγ + TNFα (10ng/ml). Media was harvested and the concentrations of CXCL9 (panels a and b), CXCL10 (panels c and d) and CXCL11 (panels e and f) were measured by ELISA. Data are presented as mean ± SEM, where * represents p<0.05, **p<0.01 and ***p<0.001.