Impact of RAGE signaling on cell mechanical properties.

<p>A, Representative epifluorescence micrographs (40X) of Phalloidine/TexasRED stained cells that exhibit actin organization, (B) histogram of the average TexasRED fluorescence that corresponds to the actin density, (C) histogram indicates cell rigidity (Young Modulus) and (D) cell heights measured by AFM of A7r5 cells stimulated for 24 hours with PBS, 1 mg/ml AGE-HSA or 1 mg/ml CML-HSA. Each bar represents 12–15 independent experiments. * <i>p</i> < 0.05 compared with PBS using one-way ANOVA followed by Dunn’s post-test.