RAGE stimulation increases NF-κB activity.

<p>A, Representative epifluorescence micrographs (20X) and (B) Histogram of the average GFP fluorescence intensities indicate NF-κB dependent GFP expression in A7r5 cells stimulated for 24 hours with PBS, 1 mg/ml AGE-HSA or 1 mg/ml CML-HSA. Each bar represents 10–12 independent experiments. * <i>p</i> < 0.05 compared with PBS using one-way ANOVA followed by Dunn’s post-test. C, Representative phase contrast micrographs (20X) indicate the morphological effects of stimulations with PBS, 1 mg/ml AGE-HSA or 1 mg/ml CML-HSA in A7r5 cells for 24 hours (n = 6).