Typical examples of chromatin profiles.

<p>(A) H3K4me3 peaks are absent in the TSS of MEG Smp_085840 (highlighted in yellow) while surrounding genes show characteristic peaks in all 4 samples. (B) Polycistronic genes Smp_038430, Smp_038420 and Smp_038410 (from right to left, highlighted in yellow) show an H3K4me3 peak only in the first gene. (C) Changes in chromatin structure in cercariae (left) and adults (right). On top predicted genes, below RNA-Seq based exon/intron structure, followed by H3K4Me3 (blue), H3K9Ac (green), H3K27Me3 (yellow) and H3K9Me3 (red), identical scale for cercariae and adults. Positions of TSS that were detected by RNA-Seq are indicated by a dotted line.