Average H3K27me3 enrichment profile of the chromosome 1 genes.

<p>X axis represents the position in bases relative to the transcriptional start site (TSS, position 0), Y axis represents the normalized mean enrichment of reads obtained after a ChIP targeting the H3K27me3 mark on (A) cercariae and (B) adults. The EpiChIP enrichment has been calculated around the TSS of the chromosome 1 transcripts obtained in our RNA-Seq experiment. It has been normalized with the same mean enrichment of reads obtained after a ChIP without antibody. The mean profile for two male biological replicates (blue) and three female biological replicates (red) are represented. The profile for each replicate is provided in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0004930#pntd.0004930.s002" target="_blank">S1 supporting</a> information (Slide 8). The same profile was obtained for the ZW linkage group.