DhL induced the expression of proteins involved in cell cycle arrest and the apoptotic response of D384 cells.

<p>D384 cells were exposed to 12.5, 15 and 17.5 μM DhL for 16 h. Total protein lysates were separated by 12–15% SDS-PAGE followed by western blot analysis with the indicated antibodies against BAX, CDKN1A, TP53, S46-p-TP53, and p139-<b>γ</b>H2AX, as shown in Panel A, and TP73 and Y99-p-TP73, as shown in Panel B. <b>α</b>-Tubulin and ß-actin were used as loading controls for total cell extracts.