Gross view and histopathology of representative hamster liver by the groups.

<p>(A) Photographs of the liver after 16 weeks of infection (a-d represents Ctrl., Cs, NDMA, and Cs+NDMA group respectively). (B) H&E stained liver sections in different groups of hamsters (original magnification ×200) (a-d represents Ctrl., Cs, NDMA, and Cs+NDMA group respectively). Normal hepatic cells and biliary triad are observed in Ctrl. Group; proliferated bile duct, periductal fibrosis, and inflammatory cells are observed in the Cs group (yellow arrow head indicates an egg of <i>C</i>. <i>sinensis</i> enlarged below left); normal findings in NDMA group; highly proliferated bile duct epithelial cells in a fibrous stroma leading to CCA in Cs+NDMA group.