Phosphorylative capacities of different NADH-linked substrate combinations.

<p>The graph shows the ability of different substrate combinations of pyruvate (5 mM), glutamate (10 mM) and malate (0.5 mM) to stimulate respiration in the presence of ADP (2.5 mM). State 1 (e_N) is used as a control state. No difference was found between state 1 respiration and the OXPHOS states of the different substrate conditions. e_N: endogenous respiration without reducing substrates or ADP (six measurements), P: pyruvate (three measurements), GM: glutamate and malate (six measurements), PM: pyruvate and malate (three measurements), PMG: pyruvate, malate and glutamate (three measurements). Fluxes are expressed as means ± SEM.