Oxygen consumption in isolated mitochondria isolated from WT and PINK1 KO mice.
- Hilary K. Siddall (407990)
- Derek M. Yellon (407991)
- Sang-Bing Ong (407992)
- Uma A. Mukherjee (407993)
- Niall Burke (407994)
- Andrew R. Hall (407995)
- Plamena R. Angelova (407996)
- Marthe H. R. Ludtmann (407997)
- Emma Deas (49268)
- Sean M. Davidson (407998)
- Mihaela M. Mocanu (407999)
- Derek J. Hausenloy (408000)
Publication date
April 2013
DOIAbstract
<p>in the presence of the (a) Complex I substrate (5 mM Malate/5 mM Glutamate) (b) Complex II substrate (succinate in the presence of rotenone) (c) The respiratory control ratio (RCR), the ratio of state 3 (ADP-stimulated) to state 4 respiration (no ADP present), which is an indication of the degree of coupling of the mitochondrial respiratory chain activity to oxidative phosphorylation.</p
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