EpCAM^low CD11b^high DCs are the main skin DC subset trafficking to the DLN after BCG infection.

<p>Frequency (<b>A</b>) and total number (<b>B</b>) of CFSE⁺ cells within defined subsets of migratory skin DCs in pLN after BCG infection. (<b>A</b>) Zebra plots showing gating strategy employed (top panel) and the frequency of CFSE⁺ cells within each, defined subset at different time points after BCG infection (bottom panels). The frequency of CFSE⁺ cells within the EpCAMl^ow CD11b^high population in BCG-draining pLN is statistically significant relative to PBS-draining pLN for all three time points analyzed. (<b>B</b>) Total number of CFSE⁺ cells within each subset as defined in (<b>A</b>). For each experiment, at least 5 mice were used for BCG-infected groups and 3 for PBS controls. Bars indicate standard error of the mean. *Denotes statistically significant differences relative to PBS-injected controls. One of three independent experiments shown.