Additional file 3: of SJP-L-5, a novel small-molecule compound, inhibits HIV-1 infection by blocking viral DNA nuclear entry

The effect of SJP-L-5 on the HIV-1 DNA flap. Figure S2. The effect of SJP-L-5 on the HIV-1 DNA flap. 293 T cells were infected with VSV-G pseudotyped NL4-3-Luc or CMVΔR8.2-Luc in the presence of SJP-L-5 (5 μg/ml, Gray) or DMSO (Black) as a negative control. The antiretroviral activity was evaluated by testing the activity of the luciferase reporter gene at 48 h post infection. Error bars indicate standard deviations of triplicate values. Statistical significance was analyzed by the Student’s t test. *** P < 0.001 versus the negative control. (TIFF 370 kb