Expression of PAX6 in ARX ko mice.

<p>(A) Immunostaining of PAX6 (green), somatostatin (red), and insulin (blue) in ARX knockout (ARX ko) and wild type (WT) E18.5 mouse pancreatic samples. Image on the right shows individual PAX6 channel showing nuclear PAX6 in wild type islet cells and lower levels of PAX6 in ARX ko tissue. (B) Immunostaining of PAX6 (green), ISL1 (red), and NKX2.2 (blue) in the same samples as in A. Inset is a ~3x enlarged portion from the region indicated by the star. Scale bar is 100 μm for all panels.