Example of a chromosome map showing differential gene expression in the telomeric regions of chromosome 11 between FCB and both FCB pfmdr1_3â˛KD and 106/1. Expression fold changes for both pairwise comparisons were plotted as a function of the chromosomal coordinates of each gene. Each circle represents a distinct gene. The dashed line delineates the threshold value of a 1.5 fold shift that was interpreted as evidence of transcriptional differences. Note that the (sub)telomeric regions of chromosome 11 are enriched in transcriptionally variable multigene families, notably var and phist genes. (PDF 129 kb
Gene expression correlation between P. falciparum genes and either pfcrt or pfmdr1. Pearson correlat...
Assessment of a possible time shift in gene expression between parasite lines. We examined the data ...
Cluster heatmap of gene expression data for pfcrt/pfmdr1 and all other genes. The hierarchical clust...
Genomic map of the pfmdr1-containing amplicon region on chromosome 5 of the FCB strain. Genes listed...
Venn diagrams depicting the number of genes that were found differentially expressed between FCB and...
Results of quantitative real time PCR to estimate gene copy numbers associated with gene expression ...
Genes with significant differential expression between 7G8 pfcrt_CTL and 7G8 pfcrt_T76K in a stage-s...
Genes (A-D) and gene sets (E-H) differentially expressed in the pfmdr1 data set. For each pairwise c...
List of genes with significant differential expression between FCB and FCB pfmdr1_3â˛KD in a stage-...
Gene set enrichment analysis for the FCB pfmdr1_3′KD vs 106/1 pairwise comparison. Gene sets that ar...
List of genes with significant differential expression between FCB and 106/1 in a stage-specific man...
List of genes within the pfmdr1-containing amplicon with associated fold change between FCB and both...
Genes (A-F, I-K) and gene sets (G-H, L-M) differentially expressed in the pfcrt data set. For each p...
Identification of genes whose expression is strongly correlated to that of both pfcrt and pfmr1. PCC...
Schema summarizing the parental and transgenic parasite lines used in this study. (A) The FCB data s...
Gene expression correlation between P. falciparum genes and either pfcrt or pfmdr1. Pearson correlat...
Assessment of a possible time shift in gene expression between parasite lines. We examined the data ...
Cluster heatmap of gene expression data for pfcrt/pfmdr1 and all other genes. The hierarchical clust...
Genomic map of the pfmdr1-containing amplicon region on chromosome 5 of the FCB strain. Genes listed...
Venn diagrams depicting the number of genes that were found differentially expressed between FCB and...
Results of quantitative real time PCR to estimate gene copy numbers associated with gene expression ...
Genes with significant differential expression between 7G8 pfcrt_CTL and 7G8 pfcrt_T76K in a stage-s...
Genes (A-D) and gene sets (E-H) differentially expressed in the pfmdr1 data set. For each pairwise c...
List of genes with significant differential expression between FCB and FCB pfmdr1_3â˛KD in a stage-...
Gene set enrichment analysis for the FCB pfmdr1_3′KD vs 106/1 pairwise comparison. Gene sets that ar...
List of genes with significant differential expression between FCB and 106/1 in a stage-specific man...
List of genes within the pfmdr1-containing amplicon with associated fold change between FCB and both...
Genes (A-F, I-K) and gene sets (G-H, L-M) differentially expressed in the pfcrt data set. For each p...
Identification of genes whose expression is strongly correlated to that of both pfcrt and pfmr1. PCC...
Schema summarizing the parental and transgenic parasite lines used in this study. (A) The FCB data s...
Gene expression correlation between P. falciparum genes and either pfcrt or pfmdr1. Pearson correlat...
Assessment of a possible time shift in gene expression between parasite lines. We examined the data ...
Cluster heatmap of gene expression data for pfcrt/pfmdr1 and all other genes. The hierarchical clust...