Cluster heatmap of gene expression data for pfcrt/pfmdr1 and all other genes. The hierarchical clustering was generated using PCC values calculated using log2-transformed and normalized expression values of 2,600 genes across 110 pairwise comparisons of 11 parasite transcriptome data sets, corresponding to all possible combinations in both directions (i.e. A vs. B and B vs. A). Squares indicate areas containing genes that are all strongly correlated or strongly anti-correlated with the expression of both pfcrt and pfmdr1. (PDF 499 kb
List of genes with significant differential expression between FCB and 106/1 in a stage-specific man...
Heatmaps showing alignment of each profiled transcriptome to that of 3D7. FFT was used to impute exp...
List of genes with significant differential expression between FCB and FCB pfmdr1_3â˛KD in a stage-...
Hierarchical clustering, which was performed using Pearson correlation coefficients between ~2600 ge...
Cluster 2 from the Hierarchical clustering, corresponds to another group of gene pairs with high Pea...
Gene expression correlation between P. falciparum genes and either pfcrt or pfmdr1. Pearson correlat...
Identification of genes whose expression is strongly correlated to that of both pfcrt and pfmr1. PCC...
Gene set enrichment analysis for the FCB pfmdr1_3′KD vs 106/1 pairwise comparison. Gene sets that ar...
Genes (A-F, I-K) and gene sets (G-H, L-M) differentially expressed in the pfcrt data set. For each p...
Venn diagrams depicting the number of genes that were found differentially expressed between FCB and...
List of genes within the pfmdr1-containing amplicon with associated fold change between FCB and both...
Genes with significant differential expression between 7G8 pfcrt_CTL and 7G8 pfcrt_T76K in a stage-s...
Gene sets with significant enrichment (orange) or depletion (blue) in 7G8 in comparison to 7G8 pfcrt...
Genomic map of the pfmdr1-containing amplicon region on chromosome 5 of the FCB strain. Genes listed...
Genes (A-D) and gene sets (E-H) differentially expressed in the pfmdr1 data set. For each pairwise c...
List of genes with significant differential expression between FCB and 106/1 in a stage-specific man...
Heatmaps showing alignment of each profiled transcriptome to that of 3D7. FFT was used to impute exp...
List of genes with significant differential expression between FCB and FCB pfmdr1_3â˛KD in a stage-...
Hierarchical clustering, which was performed using Pearson correlation coefficients between ~2600 ge...
Cluster 2 from the Hierarchical clustering, corresponds to another group of gene pairs with high Pea...
Gene expression correlation between P. falciparum genes and either pfcrt or pfmdr1. Pearson correlat...
Identification of genes whose expression is strongly correlated to that of both pfcrt and pfmr1. PCC...
Gene set enrichment analysis for the FCB pfmdr1_3′KD vs 106/1 pairwise comparison. Gene sets that ar...
Genes (A-F, I-K) and gene sets (G-H, L-M) differentially expressed in the pfcrt data set. For each p...
Venn diagrams depicting the number of genes that were found differentially expressed between FCB and...
List of genes within the pfmdr1-containing amplicon with associated fold change between FCB and both...
Genes with significant differential expression between 7G8 pfcrt_CTL and 7G8 pfcrt_T76K in a stage-s...
Gene sets with significant enrichment (orange) or depletion (blue) in 7G8 in comparison to 7G8 pfcrt...
Genomic map of the pfmdr1-containing amplicon region on chromosome 5 of the FCB strain. Genes listed...
Genes (A-D) and gene sets (E-H) differentially expressed in the pfmdr1 data set. For each pairwise c...
List of genes with significant differential expression between FCB and 106/1 in a stage-specific man...
Heatmaps showing alignment of each profiled transcriptome to that of 3D7. FFT was used to impute exp...
List of genes with significant differential expression between FCB and FCB pfmdr1_3â˛KD in a stage-...