Effects of <i>Wse</i> on lifespan.

<p>(A) Lifespan, expressed as % survival rates, of wild type (WT) and LRRK2 flies. (B) Lifespan of untreated WT compared to treated WT, only when adults (L^-/A⁺), with <i>Wse</i>, 0.1%, 1% and 10%. (C)Lifespan of untreated LRRK2 mutants compared to treated LRRK2 mutants, only when adults (L^-/A⁺), with <i>Withania somnifera</i> extract (<i>Wse)</i>, 0.1%, 1% and 10%. (D) Lifespan of untreated LRRK2 mutants compared to treated LRRK2 mutants, from their larval stage to the end of their life-cycle (L⁺/A⁺), with <i>Wse</i>, 0.1%, 1% and 10%. *indicates p<0.05 at Kaplan-Meier survival curves (Gehan-Breslow–Wilcoxon—Graph Pad Prism 5.01), (A) untreated LRRK2 compared to untreated WT, (B) untreated WT compared to treated WT and (C-D) untreated LRRK2 compared to treated LRRK2.