<p>(a) Shortened life spans in <i>m2</i> homozygous mutant flies (red) and <i>EP2372</i> heterozygous mutant flies (green) compared to control flies (<i>w</i><sup><i>1118</i></sup>, blue). (b) Shortened life spans in lansoprazole-treated flies (orange) compared to control flies (<i>w</i><sup><i>1118</i></sup>, blue). Statistical analysis is shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0139722#pone.0139722.t001" target="_blank">Table 1</a>.</p
<p>A significantly shortened lifespan was determined in the HA flies (red) as compared to NC control...
<p>* <i>P</i> value<0.01 compared to genetic matched control or vehicle control by log-rank test.</p...
Genetic studies indicate that aging is modulated by a great number of genetic pathways. We have used...
<p>(a and b) <i>m2</i> homozygous mutant flies (red) and lansoprazole-treated flies (orange) show in...
<p>(A) Lifespan analysis of conventionally reared <i>trbd</i> mutans. Using the Log-Rank and Wilcoxo...
<p><b>(A)</b> Survival curves (in %) over time of <i>PXH87</i>, <i>crq</i><sup><i>ko</i></sup>, <i>R...
<p>(A, C) Graphs showing the percentage of (A) male and (C) female flies surviving versus time in da...
<p>(a and b) <i>m2>UAS-GFP</i> reporter flies showing that <i>vha16-1</i> was highly expressed in th...
<p>(<b>A</b>): Lifespan of flies carrying two neuronal transgenes <i>G6PD</i> and <i>HQ93</i> (open ...
<p>Shown in panel A are the lifespans of <i>Drosophila</i> in the absence of drugs [control (○)]; an...
<p>Percent survival of adult female flies of indicated genotypes at 25°C. Flies had been made coisog...
<p>(A) Lifespan of adult flies lacking <i>dMRP4</i>. Survival was presented as mean of at least 300 ...
<p>(A): Lifespan, expressed as % survival rates, of wild type (WT) and <i>PINK1<sup>B9</sup></i> fli...
In order to identify genes involved in stress and metabolic regulation, we carried out a Dro-sophila...
<p>(A) Lifespan, expressed as % survival rates, of wild type (WT) and LRRK2 flies. (B) Lifespan of u...
<p>A significantly shortened lifespan was determined in the HA flies (red) as compared to NC control...
<p>* <i>P</i> value<0.01 compared to genetic matched control or vehicle control by log-rank test.</p...
Genetic studies indicate that aging is modulated by a great number of genetic pathways. We have used...
<p>(a and b) <i>m2</i> homozygous mutant flies (red) and lansoprazole-treated flies (orange) show in...
<p>(A) Lifespan analysis of conventionally reared <i>trbd</i> mutans. Using the Log-Rank and Wilcoxo...
<p><b>(A)</b> Survival curves (in %) over time of <i>PXH87</i>, <i>crq</i><sup><i>ko</i></sup>, <i>R...
<p>(A, C) Graphs showing the percentage of (A) male and (C) female flies surviving versus time in da...
<p>(a and b) <i>m2>UAS-GFP</i> reporter flies showing that <i>vha16-1</i> was highly expressed in th...
<p>(<b>A</b>): Lifespan of flies carrying two neuronal transgenes <i>G6PD</i> and <i>HQ93</i> (open ...
<p>Shown in panel A are the lifespans of <i>Drosophila</i> in the absence of drugs [control (○)]; an...
<p>Percent survival of adult female flies of indicated genotypes at 25°C. Flies had been made coisog...
<p>(A) Lifespan of adult flies lacking <i>dMRP4</i>. Survival was presented as mean of at least 300 ...
<p>(A): Lifespan, expressed as % survival rates, of wild type (WT) and <i>PINK1<sup>B9</sup></i> fli...
In order to identify genes involved in stress and metabolic regulation, we carried out a Dro-sophila...
<p>(A) Lifespan, expressed as % survival rates, of wild type (WT) and LRRK2 flies. (B) Lifespan of u...
<p>A significantly shortened lifespan was determined in the HA flies (red) as compared to NC control...
<p>* <i>P</i> value<0.01 compared to genetic matched control or vehicle control by log-rank test.</p...
Genetic studies indicate that aging is modulated by a great number of genetic pathways. We have used...