Suppression of macrophage infiltration with COX-2-selective Antagonist (NS-398).

<p>Green fluorescence from isolectin B4 indicates CNV, red fluorescence indicates F4/80-positive macrophages. Representative macrophage infiltration lesions in the PBS vehicle-treated mice (A) and NS-398-treated mice (B). Areas of F4/80-positive cells were assessed quantitatively (C). **<i>P</i><0.001 compared with vehicle-treated mice. Error bars represented ±SD. intraperitoneal vehicle, n = 15 burn spots, intraperitoneal NS-398, n = 16 burn spots, Scale bars in A, B are 200μm.