Suppressive effects of PAF-R blockage on macrophage infiltration in CNV.

<p>Immunohistochemical analysis of lesions in the choroid of vehicle- (A) or WEB2086-treated (B) mice 72 h after laser treatment. Green fluorescence from isolectin B4 indicates CNV, and red fluorescence indicates F4/80-positive macrophages. The area of F4/80-positive cells was quantified and normalized to the area of CNV (C). **<i>P</i><0.001 compared with vehicle-treated mice. Error bars indicate mean ± SD; vehicle, n = 16, WEB2086, n = 16. Experiments were conducted in triplicate with similar results. Scale bars in A and B are 200 µm.