A distribution of inflation factors of GEI statistics on human eQTL GxE GWAS data.

<p>After filtering out probes whose expression values do not follow the normal distribution, 8,666 probes are tested for associations with about 500,000 SNPs. Gene expression of each individual was measured with and without the Ox-PAPC treatment, which corresponds to the environmental exposure. About a half of individuals were chosen to represent samples exposed to the environment, and the rest of individuals represent samples unexposed to the environment. We compute the inflation factor for each probe and for each of the three methods. Boxplots are drawn with outliers (<b>A</b>) and without outliers (<b>B</b>).