Newly Annotated and Modified TcTS. (a) 735 TcTS genes annotated as “real”; full-length containing both signal peptide and GPI anchor motifs and whose amino acid translations resulted in no in-frame stop codons; (b) List of all TcTS genes; (c) List of newly annotated TcTS and those whose bounds were modified in this study. Temporary IDs were assigned to each sequence by adding “2000” followed by a unique identifier for each newly discovered sequence on a particular contig and by pre-pending “1000” to the unique identifier for each modified sequence. (d) Locations of all TcTS genes and (e) newly identified, and modified TcTS on the T. cruzi chromosomes. Nucleotide sequences are indicated as “full-length” if they encoded both a signal sequence...
Shows the description of each T. cruzi cluster of orthologous genes, named as Supra Genes (SG) in th...
Table S1. Strain information. Table S2. Densitometry of PFGE. Table S3. Sequencing and genome statis...
Table S7. NCBI accession numbers of the T. cruzi genomes and maxicircle assemblies. (DOCX 14 kb
Flowchart to determine new putative TcTS sequences. Step 1: The sequences from the 1430 annotated Tc...
Merging of trans-sialidase sequences annotated as separate genes. The region of contig “TcCLB.505267...
Architecture of Model TcTS and Mapped to 1S0I_A Crystal Structure. The model TcTS architecture (star...
TcTS genes participating in recombination in relation to gene size. The fraction of TcTS genes in ea...
Table S2. T. cruzi CL Brener single-copy gene IDs from the 794 genes recovered from all genome assem...
Figure S1. Genome assembly Completion and Integrity Analysis (GenoCIA). (A) Genome assemblies are co...
Summary of evaluation of the recombination detection pipeline with simulated data. a) false positive...
Figure S2. Boxplot of the predicted ploidy of T. cruzi TcII field isolates. The predicted ploidy of ...
Table S3. T. cruzi CL Brener single-copy gene IDs from the 701 genes used to estimate nuclear genomi...
Figure S1. Trypanosoma cruzi PATs genes amplification by PCR as analyzed by 1% agarose gel. Note the...
Table S8. List of genes used to estimate the chromosomal ploidy of the seven TcII field isolates, af...
Figure S1. Maxicircle heterozygous SNPs. To test for evidences of mitochondrial heteroplasmy, we eva...
Shows the description of each T. cruzi cluster of orthologous genes, named as Supra Genes (SG) in th...
Table S1. Strain information. Table S2. Densitometry of PFGE. Table S3. Sequencing and genome statis...
Table S7. NCBI accession numbers of the T. cruzi genomes and maxicircle assemblies. (DOCX 14 kb
Flowchart to determine new putative TcTS sequences. Step 1: The sequences from the 1430 annotated Tc...
Merging of trans-sialidase sequences annotated as separate genes. The region of contig “TcCLB.505267...
Architecture of Model TcTS and Mapped to 1S0I_A Crystal Structure. The model TcTS architecture (star...
TcTS genes participating in recombination in relation to gene size. The fraction of TcTS genes in ea...
Table S2. T. cruzi CL Brener single-copy gene IDs from the 794 genes recovered from all genome assem...
Figure S1. Genome assembly Completion and Integrity Analysis (GenoCIA). (A) Genome assemblies are co...
Summary of evaluation of the recombination detection pipeline with simulated data. a) false positive...
Figure S2. Boxplot of the predicted ploidy of T. cruzi TcII field isolates. The predicted ploidy of ...
Table S3. T. cruzi CL Brener single-copy gene IDs from the 701 genes used to estimate nuclear genomi...
Figure S1. Trypanosoma cruzi PATs genes amplification by PCR as analyzed by 1% agarose gel. Note the...
Table S8. List of genes used to estimate the chromosomal ploidy of the seven TcII field isolates, af...
Figure S1. Maxicircle heterozygous SNPs. To test for evidences of mitochondrial heteroplasmy, we eva...
Shows the description of each T. cruzi cluster of orthologous genes, named as Supra Genes (SG) in th...
Table S1. Strain information. Table S2. Densitometry of PFGE. Table S3. Sequencing and genome statis...
Table S7. NCBI accession numbers of the T. cruzi genomes and maxicircle assemblies. (DOCX 14 kb