<p>Lung tissues were stained with (A) hematoxylin and eosin (H&E) solution for histological examination (magnification, 200×). (B) Inflammation index were determined using an image analyzer. Representative photomicrographs of lung sections are shown. NC, normal-control mice (vehicle group, PBS); OVA, OVA-induced mice (control group); Mon, OVA-induced mice + montelukast (30 mg/kg) (positive-control group); GGTA-100, OVA-induced mice + GGTA (100 mg/kg); GGTA-200, OVA-induced mice + GGTA (200 mg/kg). Values are expressed as means ± SEM (n = 3 per group). Significant differences at <sup>##</sup><i>P</i> < 0.01 compared with the NC group. Significant differences at <sup>*</sup><i>P</i> < 0.05 compared with the OVA-induced group, respectively.</p
<p>(A) Histological examination of mucus secretion in lung tissue. Lung tissue was fixed, sectioned ...
<p>(A) Spleen GC level in 4L;C* mice was not different from that in the WT. GS level was accumulated...
<p>The graphs contain the GC values (mean ± SE) from 7–16 mice in each dosing cohort relative to the...
<p>Individual data were obtained using ELISA, a collagen assay, Sirius red staining (magnification, ...
<p>Individual data were obtained using ELISA. Th2 cytokines: (A) IL-4, (B) IL-5, and (C) IL-13; chem...
<p>Lung tissues were homogenized and TGF-β1/Smad-3 protein expression was determined using western b...
<p>Individual data were obtained using ELISA. (A) Total IgE and (B) OVA-specific IgE. NC, normal-con...
<p><i>A</i>: H&E staining (original magnification: x40 and x400, upper panels) and PAS staining (x40...
<p><i>A</i>: H&E staining (original magnification: x40 and x400, upper panels) and PAS staining (x40...
<p>(A) Histological examination of lung tissue was performed 48 h after the last OVA challenge. Lung...
<p>A: Lung tissues from saline-treated mice exhibited normal architectures. B: Lung tissues from LPS...
<p>On day 0 and on day 20 mice received either HBS buffer (A, C, E, G) or GPI-0100 at the indicated ...
<p>(A) Chemical structure of hGAG. (B) Representative metastatic nodules on lung tissues. B16F10 tum...
<p>Groups of wild type or B cell KO mice challenged with saline or OVA-PM were analyzed. Groups of O...
<p>(A) Photomicrograph of lung biopsies taken from a control mouse at 24 hr post treatment with c-GM...
<p>(A) Histological examination of mucus secretion in lung tissue. Lung tissue was fixed, sectioned ...
<p>(A) Spleen GC level in 4L;C* mice was not different from that in the WT. GS level was accumulated...
<p>The graphs contain the GC values (mean ± SE) from 7–16 mice in each dosing cohort relative to the...
<p>Individual data were obtained using ELISA, a collagen assay, Sirius red staining (magnification, ...
<p>Individual data were obtained using ELISA. Th2 cytokines: (A) IL-4, (B) IL-5, and (C) IL-13; chem...
<p>Lung tissues were homogenized and TGF-β1/Smad-3 protein expression was determined using western b...
<p>Individual data were obtained using ELISA. (A) Total IgE and (B) OVA-specific IgE. NC, normal-con...
<p><i>A</i>: H&E staining (original magnification: x40 and x400, upper panels) and PAS staining (x40...
<p><i>A</i>: H&E staining (original magnification: x40 and x400, upper panels) and PAS staining (x40...
<p>(A) Histological examination of lung tissue was performed 48 h after the last OVA challenge. Lung...
<p>A: Lung tissues from saline-treated mice exhibited normal architectures. B: Lung tissues from LPS...
<p>On day 0 and on day 20 mice received either HBS buffer (A, C, E, G) or GPI-0100 at the indicated ...
<p>(A) Chemical structure of hGAG. (B) Representative metastatic nodules on lung tissues. B16F10 tum...
<p>Groups of wild type or B cell KO mice challenged with saline or OVA-PM were analyzed. Groups of O...
<p>(A) Photomicrograph of lung biopsies taken from a control mouse at 24 hr post treatment with c-GM...
<p>(A) Histological examination of mucus secretion in lung tissue. Lung tissue was fixed, sectioned ...
<p>(A) Spleen GC level in 4L;C* mice was not different from that in the WT. GS level was accumulated...
<p>The graphs contain the GC values (mean ± SE) from 7–16 mice in each dosing cohort relative to the...