Dynamics and comparison of cytokine levels in mouse lung homogenates.

<p>A. Comparison of pro-inflammatory cytokines levels throughout the infection with pairs of clinical and laboratory clonal <i>Mtb</i> strains (t-test, *p<0.05). Limit of detection (LD) for IFN-γ: 0.5pg/mL, TNF-α: 0.9 pg/mL, and IL-6: 1.4 pg/mL.) Pair comparison between mice infected B). IL-10 (LD: 16.8 pg/mL) and IL-2 (LD: 0.1 pg/mL) levels in mice infected with laboratory and clinical <i>Mtb</i> pairs. Bars represent the mean values of cytokine concentration for five mice and the error bars represent the standard deviation.