Reduced cytokine production in the lung of Myd88^-/- mice during infection with D39 or D39Δ<i>cps</i>.

<p>Lung levels of TNF-α (A and B), IL-1β (C and D) and IL-6 (E and F) of wild type (WT, black bars) and Myd88^-/- mice (MyD88 KO, white bars) at 6 and 48 hours after inoculation with D39 (A/C/E) or at 6 or 24 hours post inoculation of D39Δ<i>cps</i> (B/D/F). Data are mean ± SEM (N = 6–8 mice per group at each time point). *P<0.05, **P<0.005, ***P<0.0005 vs WT mice.