Adalimumab affects the distribution of monocyte subsets.

<p>(A) Percentage of CD14+ monocytes (<i>i</i>.<i>e</i>., all monocytes) in patients treated with adalimumab (Ada), etanercept (Eta) or infliximab (Inf). *p<0.05. (B) Quantification of HLA-DR expression in CD14+ monocytes. (C) Percentage of CD14++,CD16- (classical) monocytes in patients treated with Ada, Eta or Inf. *p<0.05. (D) Quantification of HLA-DR expression in CD14++,CD16- monocytes. (E) Percentage of CD14+,CD16++ (non-classical) monocytes in patients treated with Ada, Eta or Inf. (F) Quantification of HLA-DR expression in CD14+,CD16++ monocytes. (G) Percentage of CD14++,CD16+ (intermediate) monocytes in patients treated with Ada, Eta or Inf. (H) Quantification of HLA-DR expression in CD14++,CD16+ monocytes. For all panels: R, responders; NR, non-responders; MFI, median fluorescence intensity.