<p>Simulator console displaying evolving regions of stable chronic hypoxia with many vessels in a 40 × 40 × 40 lattice. The simulation consists of five cell types—vessel (white), <i>empty</i> (blue), <i>viable</i> (red), <i>hypoxic</i> (green), and <i>necrotic</i> (orange)—and one particle type, <i>O</i><sub>2</sub>. In row 1, column 1, the cell population at this point in the simulation consists of <i>hypoxic</i> and <i>necrotic</i> cells. In rows 2-5, columns 1-3, all cell types except vessel and <i>empty</i> have fitness and other spatial statistics reported. In row 6, the concentration of <i>O</i><sub>2</sub> is reported. In column 4, rows 2-5, aggregate cell type statistics are reported in time series. Components of the console display...
<p>The ellipsoid lattice resemble the typical shape of a lymph node. Entities interact within voxels...
<p>A cross-section of a tumour spheroid is presented. Cell centres, nodes of a mesh, are represented...
<p>3D visualization of a simulation replica exhibiting <b>Stable Type 1 CNV</b> over one simulated <...
<p>Time evolution of cell populations. Left-to-right, top-to-bottom: 220 generations shown in 36 fra...
<p>Left-to-right, top-to-bottom: 150 generations shown in 36 frames (t = 1, 5, 9, 13, 17, 21, 25, 29...
<p>Left-to-right, top-to-bottom: 150 generations shown in 36 frames (t = 1, 5, 9, 13, 17, 21, 25, 29...
<p>Time evolution of: populations by cell type (top), local fitness by cell type (middle), and neigh...
<p>(A) The model includes three different cell types: stem, progenitor and differentiated. All cell ...
<p>(a) Cells are initialized as a monolayer with four endothelial cells (red) representing cross-sec...
<p>Row A) Generalized-cell type: dark green: QCancer, light green: PCancer, dark red: QStem, light r...
<p>(A) Geometric representation of cells. Cell <i>a</i>, in isolation, is modeled as a disk. Cell <i...
<p>Time evolution of: populations by cell type (top), local fitness by cell type (middle), and neigh...
Netlogo simulation of 5000 cells. Cancer cells are depicted as small arrows (red, yellow or grey fo...
<p>(<b>A</b>) Dependency of parameter κ with the percentage of passive (red dots) and refractory (bl...
<p><b>A</b>: Results of a typical run at the exponential growth phase and at equilibrium (type A cel...
<p>The ellipsoid lattice resemble the typical shape of a lymph node. Entities interact within voxels...
<p>A cross-section of a tumour spheroid is presented. Cell centres, nodes of a mesh, are represented...
<p>3D visualization of a simulation replica exhibiting <b>Stable Type 1 CNV</b> over one simulated <...
<p>Time evolution of cell populations. Left-to-right, top-to-bottom: 220 generations shown in 36 fra...
<p>Left-to-right, top-to-bottom: 150 generations shown in 36 frames (t = 1, 5, 9, 13, 17, 21, 25, 29...
<p>Left-to-right, top-to-bottom: 150 generations shown in 36 frames (t = 1, 5, 9, 13, 17, 21, 25, 29...
<p>Time evolution of: populations by cell type (top), local fitness by cell type (middle), and neigh...
<p>(A) The model includes three different cell types: stem, progenitor and differentiated. All cell ...
<p>(a) Cells are initialized as a monolayer with four endothelial cells (red) representing cross-sec...
<p>Row A) Generalized-cell type: dark green: QCancer, light green: PCancer, dark red: QStem, light r...
<p>(A) Geometric representation of cells. Cell <i>a</i>, in isolation, is modeled as a disk. Cell <i...
<p>Time evolution of: populations by cell type (top), local fitness by cell type (middle), and neigh...
Netlogo simulation of 5000 cells. Cancer cells are depicted as small arrows (red, yellow or grey fo...
<p>(<b>A</b>) Dependency of parameter κ with the percentage of passive (red dots) and refractory (bl...
<p><b>A</b>: Results of a typical run at the exponential growth phase and at equilibrium (type A cel...
<p>The ellipsoid lattice resemble the typical shape of a lymph node. Entities interact within voxels...
<p>A cross-section of a tumour spheroid is presented. Cell centres, nodes of a mesh, are represented...
<p>3D visualization of a simulation replica exhibiting <b>Stable Type 1 CNV</b> over one simulated <...