Effects of burn and iNOS deficiency on mRNA levels of inflammatory genes in mouse muscle.

<p>At 3 days after burn or sham-burn, mRNA levels of IL-1β, TNF-α, IFN-γ and TLR-4 were increased by burn in wild-type (WT) mice. Burn-induced increase in mRNA levels of these genes was attenuated in iNOS knockout (iNOS KO) mice. **P<0.01, ***P<0.001 vs. WT-Sham and iNOS KO-Sham, §P<0.05, §§P<0.01 vs. WT-Burn. n = 3 mice per group for Sham; n = 5 mice per group for Burn.