<p>Statistical powers of all the simulated QTNs in the first simulation experiment plotted against Type 1 error (in a log10 scale) for the five GWAS methods (ISIS EM-BLASSO, SCAD, EMMA, FarmCPU, and mrMLM).</p
Additional file 1: Figure S1. Comparison between E-GWAS strategy and BSLMM, MLMM, mrMLM, BLINK, or F...
<p>Power of detection for the different 2-locus models. Power was estimated as the proportion of ite...
<p>Statistical powers of QTL detection obtained with three mapping methods for the simulated dataset...
<p>A-D, KW, MLM and LM. The “Power” was defined as the detection frequency in 500 repeats for a cert...
<p>The power of the different methods to detect a QTN using a 5% significance level (based on the ob...
<p><b>A</b>) Statistical power was examined on a trait simulated from 27 causative mutations (QTNs) ...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>(A) QQ plot of -log10 p values from SNP set tests using different SNP weights under the null simu...
<p>Powers (left hand plots) are defined as the proportion of replicates (out of 1000) in which both ...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>(A) 100% causal SNVs within all genes, estimated with SKAT. (B) 100% causal SNVs within each gene...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>A set of SNPs was randomly sampled as causal QTNs for the simulated traits (0.04%, 0.05%, 0.085% ...
<p>* Multiple Testing Correction: performed via Benjamini-Yekutieli procedure with a 5% threshold.</...
Additional file 2: Figure S2. Comparison between E-GWAS strategy and BSLMM, MLMM, mrMLM, BLINK, or F...
Additional file 1: Figure S1. Comparison between E-GWAS strategy and BSLMM, MLMM, mrMLM, BLINK, or F...
<p>Power of detection for the different 2-locus models. Power was estimated as the proportion of ite...
<p>Statistical powers of QTL detection obtained with three mapping methods for the simulated dataset...
<p>A-D, KW, MLM and LM. The “Power” was defined as the detection frequency in 500 repeats for a cert...
<p>The power of the different methods to detect a QTN using a 5% significance level (based on the ob...
<p><b>A</b>) Statistical power was examined on a trait simulated from 27 causative mutations (QTNs) ...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>(A) QQ plot of -log10 p values from SNP set tests using different SNP weights under the null simu...
<p>Powers (left hand plots) are defined as the proportion of replicates (out of 1000) in which both ...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>(A) 100% causal SNVs within all genes, estimated with SKAT. (B) 100% causal SNVs within each gene...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>A set of SNPs was randomly sampled as causal QTNs for the simulated traits (0.04%, 0.05%, 0.085% ...
<p>* Multiple Testing Correction: performed via Benjamini-Yekutieli procedure with a 5% threshold.</...
Additional file 2: Figure S2. Comparison between E-GWAS strategy and BSLMM, MLMM, mrMLM, BLINK, or F...
Additional file 1: Figure S1. Comparison between E-GWAS strategy and BSLMM, MLMM, mrMLM, BLINK, or F...
<p>Power of detection for the different 2-locus models. Power was estimated as the proportion of ite...
<p>Statistical powers of QTL detection obtained with three mapping methods for the simulated dataset...