Impact of the pulsatile LDF stimulation on the neuronal ensemble Eqs (1)–(3).

<p>The time-averaged order parameter 〈<i>R</i>(<i>t</i>)〉 of the stimulated STN neurons is depicted in color ranging from 0 (blue) to 1 (red) versus the feedback delay <i>τ</i> and the stimulation intensity <i>K</i> for a strongly coupled regime (<i>g</i>_G→S = 1.7 nS/<i>μ</i>m²). The plots (A)—(D) are obtained for the stimulation signals in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0173363#pone.0173363.g008" target="_blank">Fig 8(A)–8(D)</a>, respectively, where the amplitude of the pulse train in modulated by the LDF signal <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0173363#pone.0173363.e013" target="_blank">Eq (6)</a>. The white curves in (D) delimit the parameter domains of effective desynchronization, where 〈<i>R</i>〉 < 0.25; a similar large domain of effective desynchronization can be seen on panel (B). Pulse width <i>PW</i> = 0.5 ms.