Effect of <i>H</i>. <i>pylori</i> infection on colonic PAX6 expression.

<p>(A) Immunostaining of PAX6 in the colonic mucosa of mice with <i>H</i>. <i>pylori</i> infection. PAX6 is expressed in the nuclei of colonic epithelial cells (arrows) and the number of cells expressing it is increased relative to control mice without <i>H</i>. <i>pylori</i> infection. Double immunostaining showing co-expression of GLP-1 (green) and PAX6 (red) in a colonic epithelial cell. (B) Serial counts of PAX6-posiitve cells in the colonic mucosa of mice with <i>H</i>. <i>pylori</i> infection. (C) Correlation between the numbers of PAX6- and GLP-1-positive cells. ○, control without <i>H</i>. <i>pylori</i> infection; ●, <i>H</i>. <i>pylori</i>-infected mice. All the results are expressed as the mean ± SE. Significantly greater than control at start of the experiment: *<i>P</i> <0.05.