Representative images of Grx1 and 5 staining, quantification of Grx to insulin ratio, and fluorescent intensity of db/db and db/+ islets.

<p>(a, b, e, f, i, j, m, n, q, r, u, v) Representative images taken of immunostained islets at 6, 12 and 18 weeks are shown in comparison (green: Grx1 / 5, red: insulin, bars indicate 50 <i>μ</i>m²). (c, g, k, o, s, w) Semiquantitative analysis of Grx1 / 5 staining. (d, h, l, p, t, x) Quantification of Grx 1 / 5 to insulin staining ratio. Black bars represent db/db mice, white bars represent db/+ mice, n = 3 mice, *** denotes <i>p</i> < 0.0001, ** denotes <i>p</i> < 0.005, * denotes <i>p</i> < 0.05.