Additional file 6: Figure S4. of Sophoridine induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in human pancreatic cancer cells

MOESM3 of Inhibition of endoplasmic-reticulum-stress-mediated autophagy enhances the effectiveness of chemotherapeutics on pancreatic cancer

Prakash Thakur (5495693)
Jennifer Miller-Ocuin (5437376)
Khanh Nguyen (187914)
Rina Matsuda (5495699)
Aatur Singhi (5495696)
Herbert Zeh (190079)
Nathan Bahary (4405)

July 2018

Additional file 3: Figure S3. IHC staining with anti-active Casp3 showing differentially increased a...

Additional file 1: of Disrupting SOD1 activity inhibits cell growth and enhances lipid accumulation in nasopharyngeal carcinoma

Shuai Li (65944)
Lanyan Fu (5369309)
Tian Tian (170088)
Liwen Deng (5369315)
Huangbin Li (5369312)
Weixiong Xia (383914)
Qing Gong (5369318)

June 2018

Table S1. Primers sequence for qPCR, Figure S1. Effects of PDH on cell viability of NPC cells, Figur...

Additional file 3: of Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK

Xianling Gong (5245292)
Zhihong Chen (38223)
Qinrui Han (5245295)
Chunhui Chen (119566)
Linlin Jing (5245289)
Yawei Liu (171534)
Liang Zhao (94728)
Xueqing Yao (5245286)
Xuegang Sun (338453)

May 2018

Figure S3. Apoptotic cells were significantly increased by sanguinarine treatment. Indicated CRC cel...

Additional file 7: Figure S5. of Sophoridine induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in human pancreatic cancer cells

Zihang Xu (4028183)
Fei Zhang (85787)
Chao Bai (4428472)
Chao Yao (3745564)
Hairong Zhong (4428475)
Chunpu Zou (4428478)
Xiao Chen (260187)

September 2017

The p-ERK and p-JNK expression were detected by western blot in mice tumor treated with Sophoridine....

Additional file 3: Figure S1. of Sophoridine induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in human pancreatic cancer cells

Zihang Xu (4028183)
Fei Zhang (85787)
Chao Bai (4428472)
Chao Yao (3745564)
Hairong Zhong (4428475)
Chunpu Zou (4428478)
Xiao Chen (260187)

September 2017

After pretreated with 20 μM z-VAD-fmk, a pan caspase inhibitor, for 1 h, Miapaca-S2 and PANC-1 cells...

Additional file 2: Figure S2. of SH003 induces apoptosis of DU145 prostate cancer cells by inhibiting ERK-involved pathway

Yu-Jeong Choi (3447842)
Youn Choi (3447845)
Kang Lee (320629)
Sung-Gook Cho (3447851)
Soo-Yeon Kang (3447848)
Seong-Gyu Ko (3331185)

December 2016

Regulation of protein expression of SH003 on ERK signaling pathway in LNCaP and PC-3 cells. Cells we...

Additional file 1: Figure S1. of (S)-crizotinib induces apoptosis in human non-small cell lung cancer cells by activating ROS independent of MTH1

Xuanxuan Dai (4421281)
Guilong Guo (4421284)
Peng Zou (275872)
Ri Cui (650428)
Weiqian Chen (844929)
Xi Chen (35903)
Changtian Yin (4421287)
Wei He (131453)
Rajamanickam Vinothkumar (4421290)
Fan Yang (1413)
Xiaohua Zhang (350570)
Guang Liang (206236)

September 2017

(S)-crizotinib induced cytotoxicity in NSCLC cells. Figure S2. Effect of SOD on (S)-crizotinib-induc...

Additional file 4: Figure S4. of Moxifloxacin and ciprofloxacin induces S-phase arrest and augments apoptotic effects of cisplatin in human pancreatic cancer cells via ERK activation

Vikas Yadav (218763)
Pallavi Varshney (3544619)
Sarwat Sultana (38191)
Jyoti Yadav (301590)
Neeru Saini (193663)

August 2015

CFX induced apoptosis is independent of p38 in pancreatic cancer cells. (i) Annexin V-PE assay in MI...

Additional file 1: of Phosphoglycerate dehydrogenase promotes pancreatic cancer development by interacting with eIF4A1 and eIF4E

Xuhui Ma (6323228)
Boya Li (3147633)
Jie Liu (15128)
Yan Fu (110146)
Yongzhang Luo (285528)

February 2019

Figure S1. Detection of pyruvate concentrations in different cell types. Figure S2. Reduction of ser...

Additional file 5: Figure S5. of Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine

Ming-Chen Yang (193748)
Hao-Chen Wang (3765175)
Ya-Chin Hou (382423)
Hui-Ling Tung (3765172)
Tai-Jan Chiu (502558)
Yan-Shen Shan (424776)

October 2015

OPN triggered STAT3, ERK, and NF-κB activation, but not AKT, JNK, and p38 MAPK in pancreatic cancer ...

Additional file 6: of Compound kushen injection suppresses human acute myeloid leukaemia by regulating the Prdxs/ROS/Trx1 signalling pathway

Yanxia Jin (110467)
Qian Yang (300330)
Li Liang (365079)
Lu Ding (475637)
Yuxing Liang (5990960)
Dongdong Zhang (644246)
Balu Wu (5990963)
Tian Yang (318007)
Hailing Liu (2473138)
Tingting Huang (496866)
Hui Shen (66625)
Honglei Tu (5990966)
Yunbao Pan (286272)
Yongchang Wei (3778939)
Yi Yang (116183)
Fuling Zhou (286273)

November 2018

Figure S4. Cell apoptosis and cell cycle for HL60 cells and THP-1 cells. (A) Cell apoptosis was test...

Additional file 1: of Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK

Xianling Gong (5245292)
Zhihong Chen (38223)
Qinrui Han (5245295)
Chunhui Chen (119566)
Linlin Jing (5245289)
Yawei Liu (171534)
Liang Zhao (94728)
Xueqing Yao (5245286)
Xuegang Sun (338453)

May 2018

Figure S1. Apoptosis was detected in SW480 cells treated with sanguinarine. Cells were treated with ...

Additional file 4: of Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK

Xianling Gong (5245292)
Zhihong Chen (38223)
Qinrui Han (5245295)
Chunhui Chen (119566)
Linlin Jing (5245289)
Yawei Liu (171534)
Liang Zhao (94728)
Xueqing Yao (5245286)
Xuegang Sun (338453)

May 2018

Figure S4. Z-VAD-fmk inhibited sanguinarine-induced apoptosis in CRC cells. After treatment with the...

Additional file 2: Figure S2. of Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)

Guanggai Xia (4349527)
Hongcheng Wang (4349524)
Ziliang Song (4349518)
Qingcai Meng (4349521)
Xiuyan Huang (1274364)
Xinyu Huang (679541)

August 2017

Apoptosis inhibitor Z-VAD-FMK reduced gambogic acid (GA)-induced apoptosis of pancreatic cancer cell...

Additional file 1: Figure S1. of ERK mediated upregulation of death receptor 5 overcomes the lack of p53 functionality in the diaminothiazole DAT1 induced apoptosis in colon cancer models: efficiency of DAT1 in Ras-Raf mutated cells

Reshma Thamkachy (3767449)
Rohith Kumar (465288)
K. Rajasekharan (3767446)
Suparna Sengupta (465292)

March 2016

Comparison of apoptosis in HCT116 and HCT116 p53 −/− cells treated with vinblastine : Cells were tre...

MOESM3 of Inhibition of endoplasmic-reticulum-stress-mediated autophagy enhances the effectiveness of chemotherapeutics on pancreatic cancer

Prakash Thakur (5495693)
Jennifer Miller-Ocuin (5437376)
Khanh Nguyen (187914)
Rina Matsuda (5495699)
Aatur Singhi (5495696)
Herbert Zeh (190079)
Nathan Bahary (4405)

July 2018

Additional file 3: Figure S3. IHC staining with anti-active Casp3 showing differentially increased a...

Additional file 1: of Disrupting SOD1 activity inhibits cell growth and enhances lipid accumulation in nasopharyngeal carcinoma

Shuai Li (65944)
Lanyan Fu (5369309)
Tian Tian (170088)
Liwen Deng (5369315)
Huangbin Li (5369312)
Weixiong Xia (383914)
Qing Gong (5369318)

June 2018

Table S1. Primers sequence for qPCR, Figure S1. Effects of PDH on cell viability of NPC cells, Figur...

Additional file 3: of Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK

Xianling Gong (5245292)
Zhihong Chen (38223)
Qinrui Han (5245295)
Chunhui Chen (119566)
Linlin Jing (5245289)
Yawei Liu (171534)
Liang Zhao (94728)
Xueqing Yao (5245286)
Xuegang Sun (338453)

May 2018

Figure S3. Apoptotic cells were significantly increased by sanguinarine treatment. Indicated CRC cel...

Additional file 7: Figure S5. of Sophoridine induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in human pancreatic cancer cells

Zihang Xu (4028183)
Fei Zhang (85787)
Chao Bai (4428472)
Chao Yao (3745564)
Hairong Zhong (4428475)
Chunpu Zou (4428478)
Xiao Chen (260187)

September 2017

The p-ERK and p-JNK expression were detected by western blot in mice tumor treated with Sophoridine....

Additional file 3: Figure S1. of Sophoridine induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in human pancreatic cancer cells

Zihang Xu (4028183)
Fei Zhang (85787)
Chao Bai (4428472)
Chao Yao (3745564)
Hairong Zhong (4428475)
Chunpu Zou (4428478)
Xiao Chen (260187)

September 2017

After pretreated with 20 μM z-VAD-fmk, a pan caspase inhibitor, for 1 h, Miapaca-S2 and PANC-1 cells...

Additional file 2: Figure S2. of SH003 induces apoptosis of DU145 prostate cancer cells by inhibiting ERK-involved pathway

Yu-Jeong Choi (3447842)
Youn Choi (3447845)
Kang Lee (320629)
Sung-Gook Cho (3447851)
Soo-Yeon Kang (3447848)
Seong-Gyu Ko (3331185)

December 2016

Regulation of protein expression of SH003 on ERK signaling pathway in LNCaP and PC-3 cells. Cells we...

Additional file 1: Figure S1. of (S)-crizotinib induces apoptosis in human non-small cell lung cancer cells by activating ROS independent of MTH1

Xuanxuan Dai (4421281)
Guilong Guo (4421284)
Peng Zou (275872)
Ri Cui (650428)
Weiqian Chen (844929)
Xi Chen (35903)
Changtian Yin (4421287)
Wei He (131453)
Rajamanickam Vinothkumar (4421290)
Fan Yang (1413)
Xiaohua Zhang (350570)
Guang Liang (206236)

September 2017

(S)-crizotinib induced cytotoxicity in NSCLC cells. Figure S2. Effect of SOD on (S)-crizotinib-induc...

Additional file 4: Figure S4. of Moxifloxacin and ciprofloxacin induces S-phase arrest and augments apoptotic effects of cisplatin in human pancreatic cancer cells via ERK activation

Vikas Yadav (218763)
Pallavi Varshney (3544619)
Sarwat Sultana (38191)
Jyoti Yadav (301590)
Neeru Saini (193663)

August 2015

CFX induced apoptosis is independent of p38 in pancreatic cancer cells. (i) Annexin V-PE assay in MI...

Additional file 1: of Phosphoglycerate dehydrogenase promotes pancreatic cancer development by interacting with eIF4A1 and eIF4E

Xuhui Ma (6323228)
Boya Li (3147633)
Jie Liu (15128)
Yan Fu (110146)
Yongzhang Luo (285528)

February 2019

Figure S1. Detection of pyruvate concentrations in different cell types. Figure S2. Reduction of ser...

Additional file 5: Figure S5. of Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine

Ming-Chen Yang (193748)
Hao-Chen Wang (3765175)
Ya-Chin Hou (382423)
Hui-Ling Tung (3765172)
Tai-Jan Chiu (502558)
Yan-Shen Shan (424776)

October 2015

OPN triggered STAT3, ERK, and NF-κB activation, but not AKT, JNK, and p38 MAPK in pancreatic cancer ...

Additional file 6: of Compound kushen injection suppresses human acute myeloid leukaemia by regulating the Prdxs/ROS/Trx1 signalling pathway

Yanxia Jin (110467)
Qian Yang (300330)
Li Liang (365079)
Lu Ding (475637)
Yuxing Liang (5990960)
Dongdong Zhang (644246)
Balu Wu (5990963)
Tian Yang (318007)
Hailing Liu (2473138)
Tingting Huang (496866)
Hui Shen (66625)
Honglei Tu (5990966)
Yunbao Pan (286272)
Yongchang Wei (3778939)
Yi Yang (116183)
Fuling Zhou (286273)

November 2018

Figure S4. Cell apoptosis and cell cycle for HL60 cells and THP-1 cells. (A) Cell apoptosis was test...

Additional file 1: of Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK

Xianling Gong (5245292)
Zhihong Chen (38223)
Qinrui Han (5245295)
Chunhui Chen (119566)
Linlin Jing (5245289)
Yawei Liu (171534)
Liang Zhao (94728)
Xueqing Yao (5245286)
Xuegang Sun (338453)

May 2018

Figure S1. Apoptosis was detected in SW480 cells treated with sanguinarine. Cells were treated with ...

Additional file 4: of Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK

Xianling Gong (5245292)
Zhihong Chen (38223)
Qinrui Han (5245295)
Chunhui Chen (119566)
Linlin Jing (5245289)
Yawei Liu (171534)
Liang Zhao (94728)
Xueqing Yao (5245286)
Xuegang Sun (338453)

May 2018

Figure S4. Z-VAD-fmk inhibited sanguinarine-induced apoptosis in CRC cells. After treatment with the...

Additional file 2: Figure S2. of Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)

Guanggai Xia (4349527)
Hongcheng Wang (4349524)
Ziliang Song (4349518)
Qingcai Meng (4349521)
Xiuyan Huang (1274364)
Xinyu Huang (679541)

August 2017

Apoptosis inhibitor Z-VAD-FMK reduced gambogic acid (GA)-induced apoptosis of pancreatic cancer cell...

Additional file 1: Figure S1. of ERK mediated upregulation of death receptor 5 overcomes the lack of p53 functionality in the diaminothiazole DAT1 induced apoptosis in colon cancer models: efficiency of DAT1 in Ras-Raf mutated cells

Reshma Thamkachy (3767449)
Rohith Kumar (465288)
K. Rajasekharan (3767446)
Suparna Sengupta (465292)

March 2016

Comparison of apoptosis in HCT116 and HCT116 p53 −/− cells treated with vinblastine : Cells were tre...

MOESM3 of Inhibition of endoplasmic-reticulum-stress-mediated autophagy enhances the effectiveness of chemotherapeutics on pancreatic cancer

Prakash Thakur (5495693)
Jennifer Miller-Ocuin (5437376)
Khanh Nguyen (187914)
Rina Matsuda (5495699)
Aatur Singhi (5495696)
Herbert Zeh (190079)
Nathan Bahary (4405)

July 2018

Additional file 3: Figure S3. IHC staining with anti-active Casp3 showing differentially increased a...

Additional file 1: of Disrupting SOD1 activity inhibits cell growth and enhances lipid accumulation in nasopharyngeal carcinoma

Shuai Li (65944)
Lanyan Fu (5369309)
Tian Tian (170088)
Liwen Deng (5369315)
Huangbin Li (5369312)
Weixiong Xia (383914)
Qing Gong (5369318)

June 2018

Table S1. Primers sequence for qPCR, Figure S1. Effects of PDH on cell viability of NPC cells, Figur...

Additional file 3: of Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK

Xianling Gong (5245292)
Zhihong Chen (38223)
Qinrui Han (5245295)
Chunhui Chen (119566)
Linlin Jing (5245289)
Yawei Liu (171534)
Liang Zhao (94728)
Xueqing Yao (5245286)
Xuegang Sun (338453)

May 2018

Figure S3. Apoptotic cells were significantly increased by sanguinarine treatment. Indicated CRC cel...

Additional file 6: Figure S4. of Sophoridine induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in human pancreatic cancer cells

Abstract

Extracted data

Additional file 6: Figure S4. of Sophoridine induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in human pancreatic cancer cells

Abstract

Extracted data

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