After pretreated with 20 μM z-VAD-fmk, a pan caspase inhibitor, for 1 h, Miapaca-S2 and PANC-1 cells were treated with 20 μM Sophoridine for 48 h. Apoptosis was evaluated by flow cytometry. (JPEG 537 kb
Figure S1. Detection of pyruvate concentrations in different cell types. Figure S2. Reduction of ser...
CFX induced apoptosis is independent of p38 in pancreatic cancer cells. (i) Annexin V-PE assay in MI...
Effects of AKT and MAPK inhibition on apoptosis in BT474 and MDAMB361 cells. Cell lines grown in 2D ...
After pretreated with 5 mM NAC for 2 h, cells were treated with or without 20 μM Sophoridine for ind...
The p-ERK and p-JNK expression were detected by western blot in mice tumor treated with Sophoridine....
Apoptosis inhibitor Z-VAD-FMK reduced gambogic acid (GA)-induced apoptosis of pancreatic cancer cell...
PAK1 Knock-down (KD) effects on survival and ERK expression. PAK1 KD cells were measured in the pres...
(S)-crizotinib induced cytotoxicity in NSCLC cells. Figure S2. Effect of SOD on (S)-crizotinib-induc...
Additional file 3: Figure S3. IHC staining with anti-active Casp3 showing differentially increased a...
MFX and CFX induced apoptosis is caspase-dependent in both the cell lines. Western blot of cleaved c...
Regulation of protein expression of SH003 on ERK signaling pathway in LNCaP and PC-3 cells. Cells we...
OPN triggered STAT3, ERK, and NF-κB activation, but not AKT, JNK, and p38 MAPK in pancreatic cancer ...
MFX and CFX induced apoptosis is independent of p53 status. (i) Annexin-V assay ofHCT116 p53+/+ and ...
Combined inhibition of human epidermal growth factor receptor-2 (HER2), p110Îą and Vps34 induces cel...
Comparison of apoptosis in HCT116 and HCT116 p53 −/− cells treated with vinblastine : Cells were tre...
Figure S1. Detection of pyruvate concentrations in different cell types. Figure S2. Reduction of ser...
CFX induced apoptosis is independent of p38 in pancreatic cancer cells. (i) Annexin V-PE assay in MI...
Effects of AKT and MAPK inhibition on apoptosis in BT474 and MDAMB361 cells. Cell lines grown in 2D ...
After pretreated with 5 mM NAC for 2 h, cells were treated with or without 20 μM Sophoridine for ind...
The p-ERK and p-JNK expression were detected by western blot in mice tumor treated with Sophoridine....
Apoptosis inhibitor Z-VAD-FMK reduced gambogic acid (GA)-induced apoptosis of pancreatic cancer cell...
PAK1 Knock-down (KD) effects on survival and ERK expression. PAK1 KD cells were measured in the pres...
(S)-crizotinib induced cytotoxicity in NSCLC cells. Figure S2. Effect of SOD on (S)-crizotinib-induc...
Additional file 3: Figure S3. IHC staining with anti-active Casp3 showing differentially increased a...
MFX and CFX induced apoptosis is caspase-dependent in both the cell lines. Western blot of cleaved c...
Regulation of protein expression of SH003 on ERK signaling pathway in LNCaP and PC-3 cells. Cells we...
OPN triggered STAT3, ERK, and NF-κB activation, but not AKT, JNK, and p38 MAPK in pancreatic cancer ...
MFX and CFX induced apoptosis is independent of p53 status. (i) Annexin-V assay ofHCT116 p53+/+ and ...
Combined inhibition of human epidermal growth factor receptor-2 (HER2), p110Îą and Vps34 induces cel...
Comparison of apoptosis in HCT116 and HCT116 p53 −/− cells treated with vinblastine : Cells were tre...
Figure S1. Detection of pyruvate concentrations in different cell types. Figure S2. Reduction of ser...
CFX induced apoptosis is independent of p38 in pancreatic cancer cells. (i) Annexin V-PE assay in MI...
Effects of AKT and MAPK inhibition on apoptosis in BT474 and MDAMB361 cells. Cell lines grown in 2D ...